A Case with Laron Syndrome


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Özgen İ. T. , Kutlu E. , Cesur Y. , Yesil G.

BEZMIALEM SCIENCE, cilt.7, ss.251-254, 2019 (ESCI İndekslerine Giren Dergi)

Özet

Laron syndrome (LS) is a rare disorder leading to short stature as a result of growth hormone (GH) insensitivity. It is caused by mutations in GH receptor gene and characterized by post-natal growth retardation, craniofacial abnormalities, high serum GH and low insulin-like growth factor-1 (IGF-I) levels. Several different genetic mutations have been documented up to date. In this article, a patient with LS is reported.