Biological Augmentation in Rotator Cuff Repair: Scaffolds

Bilgin E., Kapıcıoğlu M., Bilsel İ. K.

in: Massive and Irreparable Rotator Cuff Tears , Nuno Sampaio GomesLadislav KovačičFrank MartetschlägerGiuseppe Milano, Editor, Springer, London/Berlin , Berlin, pp.55-66, 2020

  • Publication Type: Book Chapter / Chapter Vocational Book
  • Publication Date: 2020
  • Publisher: Springer, London/Berlin 
  • City: Berlin
  • Page Numbers: pp.55-66
  • Editors: Nuno Sampaio GomesLadislav KovačičFrank MartetschlägerGiuseppe Milano, Editor
  • Bezmialem Vakıf University Affiliated: Yes


Rotator cuff (RC) tears are a considerable reason of shoulder disability in both the young and elderly population. Although instrumentation methods and surgical techniques have been improving, the failure rates remain still high after tendon repairs attributed to large tear size, increased age, poor tendon quality and fatty infiltration of the RC muscle.

To enhance the healing potential of RC and improve outcomes after repair, various augmentation methods have been introduced over the past two decades. Growth factors, stem cell therapies and scaffolds are the main augmentation approaches. The aim of these procedures is to enhance the healing potential of the repair construct and, simultaneously, help the restoration of the native tendon-to-bone interface.

This chapter will focus on scaffold devices and their role in the augmentation of RC repair. The biomechanical properties of the scaffolds, their efficacy, outcomes and complications based on both preclinical and clinical studies are discussed. An overview of the future trends in scaffold augmentation for RC surgery is presented in light of the current literature.