Histopathological Features of Gastrointestinal Stromal Tumors and the Contribution of DOG1 Expression to the Diagnosis

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GÜLER B., Ozyilmaz F., Tokuc B., Can N., Tastekin E.

BALKAN MEDICAL JOURNAL, vol.32, no.4, pp.388-396, 2015 (SCI-Expanded, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 32 Issue: 4
• Publication Date: 2015
• Doi Number: 10.5152/balkanmedj.2015.15912
• Journal Name: BALKAN MEDICAL JOURNAL
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.388-396
• Open Archive Collection: AVESIS Open Access Collection
• Bezmialem Vakıf University Affiliated: Yes

Abstract

Background: Gastrointestinal stromal tumors (GIST) have KIT or platelet-derived growth factor receptor a (PDGFR alpha) mutations affecting receptor tyrosine kinase activity and do not benefit from classic treatment regimens.