Histopathological Features of Gastrointestinal Stromal Tumors and the Contribution of DOG1 Expression to the Diagnosis

GÜLER B. , Ozyilmaz F., Tokuc B., Can N., Tastekin E.

BALKAN MEDICAL JOURNAL, vol.32, no.4, pp.388-396, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.5152/balkanmedj.2015.15912
  • Title of Journal : BALKAN MEDICAL JOURNAL
  • Page Numbers: pp.388-396

Abstract

Background: Gastrointestinal stromal tumors (GIST) have KIT or platelet-derived growth factor receptor a (PDGFR alpha) mutations affecting receptor tyrosine kinase activity and do not benefit from classic treatment regimens.