WRIGHTIADIONE FROM WRIGHTIA-TOMENTOSA

LIN L., TOPCU G., LOTTER H., RUANGRUNGSI N., WAGNER H., PEZZUTO J., ...More

PHYTOCHEMISTRY, vol.31, no.12, pp.4333-4335, 1992 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 12
  • Publication Date: 1992
  • Doi Number: 10.1016/0031-9422(92)80469-u
  • Journal Name: PHYTOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4333-4335
  • Keywords: WRIGHTIA-TOMENTOSA, APOCYNACEAE, ISOFLAVONE, WRIGHTIADIONE, SELECTIVE INEPT NMR SPECTROSCOPY, X-RAY CRYSTALLOGRAPHY
  • Bezmialem Vakıf University Affiliated: No

Abstract

A novel isoflavone wrightiadione, was isolated from Wrightia tomentosa. Determination of the carbon framework was based on the interpretation of NMR and mass spectral data, and the structure was confirmed by X-ray analysis. This compound displays cytotoxic activity against the murine P388 lymphocytic leukemia cell line (ED50, 1.1 mug ml-1).