IN VITRO GENOTOXICITY OF CALCIUM PHOSPHATE-BASED BONE SUBSTITUTE MATERIAL ON HUMAN PERIPHERAL MONONUCLEAR LEUKOCYTES

Altay M. A., Erturk C., KOÇYİĞİT A., Taskin A., Celik H.

ACTA MEDICA MEDITERRANEA, cilt.29, sa.4, ss.723-729, 2013 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2013
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.723-729
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Background and aim: Calcium phosphate-based bone substitute materials, also called calcium phosphate cements (CPCs), are widely used in orthopedic surgery. However, the reported results regarding the genotoxicity using these materials are inadequate in literature. We evaluated the DNA damaging effects of a CPC on peripheral mononuclear leukocyte cultures.