Is signal peptide-CUB-EGF domain-containing protein1 a diagnostic biomarker in patients with hypertensive crises

KARABACAK M., YIGIT M., TURKDOGAN K. A., YIGIT E., Selek S.

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, vol.61, no.3, pp.513-522, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.3233/ch-141917
  • Journal Name: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.513-522
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

BACKGROUND: Platelet activation might play a significant role in the pathophysiology of cardiovascular and cerebrovascular events in hypertension (HT). Signal peptide-CUB-EGF domain-containing protein1 (SCUBE1), an indicator of platelet activation, is increased in HT. The aim of this study was to investigate the SCUBE1 in patients with hypertensive crises.