ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, vol.35, pp.2050-2062, 2011 (Journal Indexed in SCI)
Article / Article
Title of Journal :
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Ethanol Abuse, Ethanol Withdrawal, Rats, Hippocampus, FT-IR Spectroscopy, TRANSFORM-INFRARED-SPECTROSCOPY, PROTEIN SECONDARY STRUCTURE, PHYSICAL-DEPENDENCE, LIPID-PEROXIDATION, ALCOHOL, BRAIN, INDUCTION, LIVER, TOLERANCE, MEMORY
Background: The numerous adverse effects of ethanol abuse and ethanol withdrawal on biological systems are well documented. Conversely, the understanding of the molecular mechanisms underlying these pathological effects is still incomplete. This study was undertaken to investigate the effects of short-term chronic ethanol administration and ethanol withdrawal on the molecular structure and function of hippocampal tissue, a brain region important for mnemonic processes and known to be highly susceptible to ethanol intoxication.