RELATIONSHIP BETWEEN METABOLIC SYNDROME AND INFLAMMATION IN PERITONEAL DIALYSIS PATIENTS


Borazan A., Ucar E., Gursu M., Emir I., Ozturk Y.

EUROPEAN JOURNAL OF INFLAMMATION, vol.10, no.2, pp.203-207, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1177/1721727x1201000205
  • Journal Name: EUROPEAN JOURNAL OF INFLAMMATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.203-207
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

We aimed to investigate the relationship between inflammation and metabolic syndrome as defined by the National Cholesterol Education Program Adults Treatment Panel III (NCEP-ATP III) diagnostic criteria in peritoneal dialysis patients. Ninety-four patients treated with peritoneal dialysis were included in the study. Patients' age, sex, weight, waist circumference, arterial blood pressure, fasting blood glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, C-reactive protein, albumin, uric acid and fibrinogen levels were recorded. Fourty-one patients diagnosed with metabolic syndrome and 53 peritoneal dialysis patients without metabolic syndrome were identified. In the metabolic syndrome group mean decrease in serum albumin and mean increase in C-reactive protein and fibrinogen was significantly different from the other group (p < 0.05, p < 0.05, p < 0.05, respectively). When gender, diabetes mellitus, and hypertension status were evaluated, the difference was not significant (p > 0.05). Peritoneal dialysis patients with metabolic syndrome should also be assessed for inflammation.