Integrase inhibitor-based antiretroviral treatments decrease oxidative stress caused by HIV infection

AKKOYUNLU Y., KOÇYİĞİT A., OKAY G., Guler E. M., ASLAN T.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.24, no.23, pp.12389-12394, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 23
  • Publication Date: 2020
  • Doi Number: 10.26355/eurrev_202012_24033
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.12389-12394
  • Keywords: Oxidative stress, HIV infection, Integrase inhibitor-based antiretroviral treatment, SERUM MALONDIALDEHYDE, REDOX, INDIVIDUALS, LYMPHOCYTES, CHILDREN, PROFILE, PLASMA
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

OBJECTIVE: Several chronic illnesses, including HIV infection are associated with oxidative stress. In addition to HIV itself, some antiretrovirals also increase oxidative stress while decreasing viral replication. To investigate the alterations in oxidative stress parameters and thiol-disulphide homeostasis in people living with HIV who were receiving integrase inhibitor-based antiretroviral therapy.