Current HPLC Methods for Assay of Nano Drug Delivery Systems


Tekkeli S. E. K. , KIZILTAS M. V.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, cilt.17, ss.1588-1594, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 17 Konu: 13
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1568026616666161222112305
  • Dergi Adı: CURRENT TOPICS IN MEDICINAL CHEMISTRY
  • Sayfa Sayısı: ss.1588-1594

Özet

In nano drug formulations the mechanism of release is a critical process to recognize controlled and targeted drug delivery systems. In order to gain high bioavailability and specificity from the drug to reach its therapeutic goal, the active substance must be loaded into the nanoparticles efficiently. Therefore, the amount in biological fluids or tissues and the remaining amount in nano carriers are very important parameters to understand the potential of the nano drug delivery systems. For this aim, suitable and validated quantitation methods are required to determine released drug concentrations from nano pharmaceutical formulations.