3. International Confereans on Covid 19 Studies, Ankara, Türkiye, 25 - 27 Aralık 2020, ss.1-36
SARS-CoV-2 emerged in Wuhan, China in 2019, and has taken hold in entire world in a short time. This virus, identified "Coronavirus Disease-19 (COVID-19)" by the World Health Organization (WHO), causes severe acute respiratory distress syndrome. The number of people infected with the virus increases day by day and this situation is the reason for people's deaths. COVID-19 binding to angiotensin-converting enzyme 2 (ACE2) and spreads through the respiratory tract. COVID-19 is an RNA virus and this virus shows cough, fever and flu-like symptoms similar to other coronaviruses. These symptoms might be seen in entire age groups, but the elderly and the individuals who have chronic disease history are defined as a high-risk group. After severe pneumonia, the virus can lead to acute respiratory distress syndrome and multiple organ failure, causing death in infected individuals. There is no specific medicine or vaccine to treat COVID-19. In order to protect against this virus, it is necessary to wear a mask, pay attention to hand hygiene and social distance. Because of the fact that there is no medical treatment or protection procedure, people can tend to utilize herbal remedies by acquiring immunity to viruses. Ginger (Zingiber officinale) is one of these medicinal plants. Ginger has been utilized due to various treatments of diseases for a long time in alternative medicine. These properties should be provided by an ideal anti-COVID-19 agent; being safe for patients, ensuring antiviral immunity, increasing repair of tissue and demonstrating strong antiviral effects. It is known that the ginger that ensures whole these criteria, additionally, contains tumor necrosis factor-a (TNF-a) which defined as cytokine of anti-influenza. It has been reported that the ginger which not only increases the immun response, but also decreases viral replication. Ginger has the property of inhibiting prostaglandin, leukotriene biosynthesis and cyclooxygenase, lipoxygenase activities. in-silico studies conducted according with these known effects have also shown that the active ingredients of ginger have encouraging effects against COVID-19. It has been observed that the use of ginger in various mixtures has positive effects on COVID-19 patients. This study, will discuss the impacts on the course of the disease the ginger and the mixture which contains ginger, used in the treatment COVID-19.