A Treatment-Response Comparison Study of Resting-State Functional Magnetic Resonance Imaging Between Standard Treatment of SSRI and Standard Treatment of SSRI Plus Non-dominant Hand-Writing Task in Patients With Major Depressive Disorder

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BOYRAZ R. K., KIRPINAR İ., YILMAZ O., Ozyurt O., KILIÇARSLAN T., ARALAŞMAK A.

FRONTIERS IN PSYCHIATRY, vol.12, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12
  • Publication Date: 2021
  • Doi Number: 10.3389/fpsyt.2021.698954
  • Journal Name: FRONTIERS IN PSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, EMBASE, Psycinfo, Directory of Open Access Journals
  • Keywords: major depressive disorder, resting-state functional magnetic resonance imaging, non-dominant hand-writing exercise, treatment response, comparison study, EYE-MOVEMENT DESENSITIZATION, DEFAULT MODE NETWORK, MOOD REGULATING CIRCUIT, REGIONAL HOMOGENEITY, ANTIDEPRESSANT TREATMENT, FREQUENCY FLUCTUATION, SUICIDE ATTEMPTERS, PREFRONTAL CORTEX, NEURAL ACTIVITY, CONNECTIVITY
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background: Researches have recently shifted from functional/structural imaging studies to functional connectivity (FC) studies in major depressive disorder (MDD). We aimed to compare treatment response of two treatment groups before and after treatment, in terms of both with psychiatric evaluation scales and resting-state functional connectivity (RSFC) changes in order to objectively demonstrate the possible contribution of the non-dominant hand-writing exercise (NHE) effect on depression treatment.