Kounis syndrome, a cause of chest pain to keep in mind, may be associated with E148Q mutation


Saylan B., Cevik A., Firat C. K.

HONG KONG JOURNAL OF EMERGENCY MEDICINE, cilt.19, ss.278-282, 2012 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 19 Konu: 4
  • Basım Tarihi: 2012
  • Dergi Adı: HONG KONG JOURNAL OF EMERGENCY MEDICINE
  • Sayfa Sayısı: ss.278-282

Özet

Chest pain is among the leading complaints in paediatric emergency. The Kounis syndrome is a rare allergic coronary vasospasm, which can cause angina and myocardial infarction. Even though organic causes are infrequent as a cause of chest pain in children, it is important to know when and how this symptom may become serious. We reported a patient who had been admitted with chest pain to the emergency department, hospitalised for coronary vasospasm and diagnosed to have Kounis syndrome and heterozygous E148Q mutation. The finding could be a coincidental finding, but considering of the heterogeneity and phenotypic differences in FMF, the relationship between E148Q mutation and Kounis syndrome should be explored further. (Hong Kong j.emerg.med. 2012;19:278-282)