Kounis syndrome, a cause of chest pain to keep in mind, may be associated with E148Q mutation


Saylan B., Cevik A., Firat C. K.

HONG KONG JOURNAL OF EMERGENCY MEDICINE, vol.19, no.4, pp.278-282, 2012 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2012
  • Title of Journal : HONG KONG JOURNAL OF EMERGENCY MEDICINE
  • Page Numbers: pp.278-282

Abstract

Chest pain is among the leading complaints in paediatric emergency. The Kounis syndrome is a rare allergic coronary vasospasm, which can cause angina and myocardial infarction. Even though organic causes are infrequent as a cause of chest pain in children, it is important to know when and how this symptom may become serious. We reported a patient who had been admitted with chest pain to the emergency department, hospitalised for coronary vasospasm and diagnosed to have Kounis syndrome and heterozygous E148Q mutation. The finding could be a coincidental finding, but considering of the heterogeneity and phenotypic differences in FMF, the relationship between E148Q mutation and Kounis syndrome should be explored further. (Hong Kong j.emerg.med. 2012;19:278-282)