An Intramucosal Mucinous Adenocarcinoma Arising From A Gastric Hyperplastic Polyp

Pasaoglu E., Gucin Z.

ISTANBUL MEDICAL JOURNAL, vol.18, no.1, pp.50-52, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.5152/imj.2016.57689
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.50-52
  • Bezmialem Vakıf University Affiliated: Yes


Hyperplastic polyps constitute 75% of all gastric polyps. Most of them are innocent lesions and are smaller than 1 cm. They develop as a consequence of an exaggerated mucosal response to tissue injury and inflammation on the basis of chronic gastritis. A 69-year-old male was admitted to the Gastroenterology Clinic with complaints of abdominal pain and vomiting. Gastroscopy showed a polyp that was 2 cm in its greatest dimension. A histopathologic examination of this lesion revealed adenocarcinoma infiltration in the mucosa. Subtotal gastrectomy was performed. Macroscopically, a polyp with a stalk was seen in the antrum; microscopically, it was consisted with a hyperplastic polyp. In the polyp, a few foci of infiltrative glands embedded in the mucinous matrix were noticed in the lamina propria, and the patient was diagnosed as intramucosal mucinous adenocarcinoma arising from a gastric hyperplastic polyp. Because of the risk of carcinoma development, which is rare, all hyperplastic polyps should be completely excised, and a histopathologic examination should be carefully performed.