Can Visual Hallucinations be among the Neuropsychological Manifestations of Systemic Mastocytosis?: A Geriatric Case

Kilic Ö. , Yilmaz U. E. , Komesli Z., Ercan A. C. , Cetiner M.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.30, sa.3, ss.123-125, 2020 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 30 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5455/pcp.20200316094036
  • Sayfa Sayıları: ss.123-125


Mast cells are considered sensors of environmental and emotional stress, exist in all body parts and are related to the pathway from stress to inflammation. Mastocytosis defines a rare disease characterized by the accumulation of abnormal mast cells in multiple organs. Here, we present a 77-year-old woman with a background of aggressive systemic mastocytosis who developed impaired cognition, depression, anxiety, visual hallucinations, delusions, and insomnia. Symptoms alleviated only after initiating midostaurin, a tyrosine kinase inhibitor. Systemic mastocytosis should be kept in mind when visual hallucinations are concomitant with chronic or recurrent multi-system disturbances and do not benefit from treatment as usual.