Role of 18F-FDG PET/CT imaging in the strategic selection of the accessory spleen as a biopsy site for definitive lymphoma diagnosis in a 67-year-old man: A Case report


Erdogan E. B., Çetin G., Yozgat C. Y., Koca S., Aydin M.

MEDECINE NUCLEAIRE, cilt.2026, sa.1, ss.1-3, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Vaka Takdimi
  • Cilt numarası: 2026 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1016/j.mednuc.2025.09.010
  • Dergi Adı: MEDECINE NUCLEAIRE
  • Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), EMBASE
  • Sayfa Sayıları: ss.1-3
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

The role of 18F-FDG PET/CT in lymphoma staging and treatment response assessment is well established in the literature. Beyond these conventional applications, it can also serve as a powerful tool for guiding biopsy decisions in diagnostically challenging cases. We present the case of a 67-year-old man with suspected lymphoma, in whom initial diagnostic procedures—including bone marrow aspiration—failed to yield conclusive results. A multidisciplinary team utilized 18F-FDG PET/CT to identify an accessory spleen exhibiting metabolic activity comparable to the primary spleen. Given its accessibility and diagnostic potential, the accessory spleen was surgically excised, leading to a definitive diagnosis of mantle cell lymphoma. This case underscores the strategic role of PET/CT in biopsy site selection, offering a safer and less invasive diagnostic alternative and reinforcing its crucial role in lymphoma management.