International journal of laboratory hematology, vol.43, pp.1093-1103, 2021 (Peer-Reviewed Journal)
Article / Article
International journal of laboratory hematology
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ALL, biomarker, gene expression, LEF1, prognosis
Introduction The lymphoid enhancer factor 1 (LEF1) is a DNA-binding transcription factor that functions in the Wnt signaling pathway. Increased LEF1 activity is associated with progression of several types of cancer including leukemia. Here, we investigated LEF1 isoform expression and genomic variations in acute lymphoblastic leukemia (ALL).