No Harmful Effect of Dialysis-Induced Hypotension on the Myocardium in Patients Who Have Normal Ejection Fraction and a Negative Exercise Test


Fotbolcu H. , Oduncu V., Gurel E., Cevik C., Erkol A., Ozden K., ...More

KIDNEY & BLOOD PRESSURE RESEARCH, vol.35, no.6, pp.671-677, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1159/000342755
  • Title of Journal : KIDNEY & BLOOD PRESSURE RESEARCH
  • Page Numbers: pp.671-677

Abstract

Background: We investigated the effects of dialysis-induced hypotension (DIH) on the myocardium of patients who have a normal ejection fraction and normal treadmill stress tests. Methods: This study included 26 end-stage renal disease (ESRD) patients with DIH, 30 ESRD patients without DIH (non-DIH), and 30 control subjects. Mitral-myocardial systolic velocity (MSV), the mitral E'/A' ratio, the left ventricle filling pressure index (E/E' ratio), tricuspid-MSV, and the tricuspid E'/A' ratio were calculated. Results: Biventricular systolic and diastolic functions were impaired in dialysis patients. The mitral and tricuspid MSV were similar between DIH and non-DIH patients (8.03 +/- 0.90 cm/s vs. 8.31 +/- 1.68 cm/s, p = 0.896, and 13.27 +/- 2.97 cm/s vs. 13.15 +/- 2.37 cm/s, p = 0.980). Mitral and tricuspid E'/A' were similar between DIH and non-DIH patients. (1.30 +/- 0.53 vs. 1.16 +/- 0.56, p = 0.695, and 0.70 +/- 0.24 vs. 0.68 +/- 0.33, p = 0.976). Likewise, the E/E' ratio was similar between DIH and non-DIH patients (8.20 +/- 2.83 vs. 8.28 +/- 2.53, p = 0.990). Conclusion: Although biventricular systolic and diastolic function is impaired in dialysis patients compared to controls, DIH episodes did not have an adverse effect on the myocardial functions. Copyright (C) 2012 S. Karger AG, Basel