Evaluation of neurological examination, SEP results, MRI results, and lesion levels in patients who had been operated for myelomeningocele

Canaz G., Canaz H., Erdogan E. T., Alatas I., Emel E., Matur Z.

JOURNAL OF PEDIATRIC NEUROSCIENCES, vol.15, no.4, pp.393-401, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.4103/jpn.jpn_77_19
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE
  • Page Numbers: pp.393-401
  • Keywords: Ambulation, myelomeningocele, somatosensory evoked potentials, spina bifida, SOMATOSENSORY-EVOKED-POTENTIALS, QUALITY-OF-LIFE, TETHERED CORD, SPINAL DYSRAPHISM, CHILDREN, AMBULATION
  • Bezmialem Vakıf University Affiliated: No


Objective: Myelomeningocele is the most severe and the most frequent form of spina bifida. Most of the myelomeningocele patients undergo operations in new-born age. In terms of life quality and rehabilitation, follow-up's of these patients in the growth and development period after the operation is critical. In our study, our aim is to emphasize the correlation of SEP results with MRI results and clinical features of the myelomeningocele patients. Materials and Methods: In our study, we included 36 patients who had undergone myelomeningocele operation and have been followed-up in Istanbul Bilim University Florence Nightingale Hospital, Spina Bifida Research and Treatment Centre. Posterior tibial nerve SEP was performed on each patient and neurological examinations were done in the same session. Results were compared with clinical functional lesion levels, levels of fusion defect and ambulation levels. In order to evaluate SEP results, we used age-related reference values from Boor et al.'s study in 2008. Patients were grouped as normal, unilaterally prolonged, bilaterally prolonged, unilaterally lost, and bilaterally lost. Results: The correlations of posterior tibial nerve SEP results were significant with ambulation levels (r = 0.428, P < 0.01), clinical functional lesion levels (r = 0.477, P < 0.01) and fusion defect levels (r = -0.528 P < 0.05). The lumbar SEP results were only significantly correlated with functional lesion levels (r = 0.443 P < 0.05). Conclusions: Radiological studies are insufficient when evaluating the functionality of the central nervous system. To fully evaluate the functionality and watch the neurological development with accuracy, especially in operated patients, electrophysiological studies should be an indispensable part of myelomeningocele follow-ups.