Retinal sensitivity improvement after intravitreal triamcinolone acetonide injection for macular edema secondary to branch retinal vein occlusion

SENTURK F., OZDEMIR H., KARACORLU M., KARACORLU S. A., Uysal O.

INDIAN JOURNAL OF OPHTHALMOLOGY, vol.61, no.1, pp.3-7, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.4103/0301-4738.105048
  • Journal Name: INDIAN JOURNAL OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3-7
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Purpose: To evaluate the effect of intravitreal triamcinolone acetonide (IVTA) on retinal sensitivity in cases of macular edema(ME) secondary to branch retinal vein occlusion (BRVO). Materials and Methods: Total of 14 eyes of 14 cases of BRVO were included in this prospective study. In each eye, at baseline and 1, 3, and 6 months after IVTA injection, logMAR visual acuity, central 4 degrees retinal sensitivity by MP-1 microperimetry, and optical coherence tomography foveal thickness were assessed. Results: Cases ages ranged from 60 to 79 years (mean 68 +/- 8 years). At 1, 3, and 6 months, the logMAR visual acuity had increased from 0.71 +/- 0.21 to 0.42 +/- 0.21, 0.46 +/- 0.30, and 0.46 +/- 0.27; the mean foveal thickness had decreased from 540 +/- 88 mu m to 254 +/- 51 mu m, 288 +/- 84 mu m, and 280 +/- 91 mu m; and the mean retinal sensitivity had increased from 4.7 +/- 2.5 dB to 7.9 +/- 2.7 dB, 8.2 +/- 3.6 dB, and 8.3 +/- 4.6 dB, respectively. Conclusion: In eyes with ME secondary to BRVO, IVTA injections result in a significant increase in not only the visual acuity but also the central 4 degrees retinal sensitivity in 6 months follow-up.