Functional analysis reveals differential effects of glutamate and MCH neuropeptide in MCH neurons

Schneeberger M., Tan K., Nectow A. R., Parolari L., Caglar C., Azevedo E., ...More

MOLECULAR METABOLISM, vol.13, pp.83-89, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13
  • Publication Date: 2018
  • Doi Number: 10.1016/j.molmet.2018.05.001
  • Journal Name: MOLECULAR METABOLISM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.83-89
  • Bezmialem Vakıf University Affiliated: No

Abstract

Objectives: Melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus (LH) regulate food intake and body weight, glucose metabolism and convey the reward value of sucrose. In this report, we set out to establish the respective roles of MCH and conventional neurotransmitters in these neurons.