After the first clinical application of distraction osteogenesis (DO) to correct mandibular deformity was reported in 1992, various applications such as maxillary or midface advancement, temporomandibular joint reconstruction, alveolar augmentation, and mandibular widening have been described in the oral and maxillofacial region. Block et al and Altuna et al first examined anterior segmental DO experimentally in the maxilla and reported successful results. After these studies, DO has been used clinically for the total advancement of the maxilla or midface. But no clinical application of DO for maxillary anterior segmental advancement was found by a review of the literature in English. In this article, we present a case with a skeletal Class III abnormality resulting from a maxillary deficiency, which was treated by using anterior segmental DO.