Can an Immunohistochemistry Method Differentiate Intestinal Tuberculosis from Crohn's Disease in Biopsy Specimens?


Ince A. T. , GUNES P., SENATES E., SEZIKLI M., TIFTIKCI A., OVUNC O.

DIGESTIVE DISEASES AND SCIENCES, vol.56, no.4, pp.1165-1170, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1007/s10620-010-1399-7
  • Title of Journal : DIGESTIVE DISEASES AND SCIENCES
  • Page Numbers: pp.1165-1170

Abstract

It is sometimes difficult to diagnose whether a patient has intestinal tuberculosis or Crohn's disease because both have similar clinical, pathologic, and endoscopic features. However, their therapies are completely different and a mistake in diagnosis can result with deterioration. Many laboratory methods for the diagnosis of tuberculosis require considerable time to receive a diagnostic result. We wanted to evaluate whether an immunohistochemical tuberculosis staining method can be helpful for faster differentiation of biopsy materials.