Can an Immunohistochemistry Method Differentiate Intestinal Tuberculosis from Crohn's Disease in Biopsy Specimens?

Ince A. T., GUNES P., SENATES E., SEZIKLI M., TIFTIKCI A., OVUNC O.

DIGESTIVE DISEASES AND SCIENCES, vol.56, no.4, pp.1165-1170, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1007/s10620-010-1399-7
  • Journal Name: DIGESTIVE DISEASES AND SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1165-1170
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

It is sometimes difficult to diagnose whether a patient has intestinal tuberculosis or Crohn's disease because both have similar clinical, pathologic, and endoscopic features. However, their therapies are completely different and a mistake in diagnosis can result with deterioration. Many laboratory methods for the diagnosis of tuberculosis require considerable time to receive a diagnostic result. We wanted to evaluate whether an immunohistochemical tuberculosis staining method can be helpful for faster differentiation of biopsy materials.