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IRANIAN RED CRESCENT MEDICAL JOURNAL, vol.18, no.2, 2016 (Journal Indexed in SCI)
Introduction: Idiopathic systemic capillary leak syndrome (ISCLS) is rarely seen, and presents with recurrent episodes of hypotension, shock, hemoconcentration, and hypoproteinemia. The main pathology is the dysfunction of the vascular endothelium, and it is characterized by an increase of capillary permeability that is accompanied by the loss of intravascular fluid and protein.