Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents

Torun, EMEL; Gokce, ABDUSSELİM; Ozgen, İLKER; Aydin, SİNEM; Cesur, Yaşar

doi:10.1515/jpem-2013-0337

Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents

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Torun E., Gokce S., Ozgen I. T., Aydin S., Cesur Y.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, vol.27, pp.667-675, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 27
Publication Date: 2014
Doi Number: 10.1515/jpem-2013-0337
Journal Name: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.667-675
Keywords: hepatosteatosis, paraoxonase, total antioxidant stress, total oxidant stress, INSULIN-RESISTANCE, GENE POLYMORPHISMS, ANTIOXIDANT STATUS, LIPOPROTEINS, PARAMETERS, THERAPY, HEALTHY, GLUCOSE
Bezmialem Vakıf University Affiliated: Yes

Abstract

Objective: Oxidative stress has been reported to be involved in the pathogenesis of metabolic disorders related with obesity. The aim of the study was to investigate the association of oxidative stress and paraoxonase activities with non-alcoholic fatty liver disease (NAFLD) as well as metabolic syndrome.