Cardia localized inflammatory fibroid polyp: A rare case report

Ulutas P. O. D., Sayar H., Bulbuloglu E., Gurbuz E., Kizildag B.

EUROPEAN JOURNAL OF THERAPEUTICS, vol.21, no.3, pp.215-218, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5455/gmj-30-172343
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.215-218
  • Keywords: Inflammatory fibroid polyp, cardia, CD34
  • Bezmialem Vakıf University Affiliated: No


Inflammatory fibroid polyp (Vanek's tumor) is a rare benign polypoid lesion of the gastrointestinal tract. It often varies between 1-3 cm in diameter. It is usually seen in 60-70 years. Microscopically, proliferate spindle cells which localized around the vessels concentrically and eosinophil-rich inflammatory infiltrate are seen. In the differential diagnosis, many benign mesenchymal tumors of gastrointestinal tract, especially gastrointestinal stromal tumor, should be considered. 70 year old male patient, admitted with epigastric pain, nausea, fever after eating, had normal laboratory values except anemia. Contrast-enhanced computed tomography revealed a polypoid mass about 4 cm in diameter in the cardia and he was operated on suspicion of gastrointestinal stromal tumor. In the microscopic examination of excision material, numerous small and large vein structures, spindle cell proliferation and eosinophil-rich inflammatory infiltrate were observed. Immunohistochemically, CD117, CD34, smooth muscle actin, desmin, S-100, cytokeratin, DOG 1 were negative, Vimentin was strongly positive and Ki-67 proliferation index was 2%. The diagnose was "inflammatory fibroid polyp". The case is presented because of the unusually localization, large diameter, its rare occurrence and the potential risk of confusion with gastrointestinal stromal tumor.