A Case of Chronic Lymphocytic Leukemia in Two Brothers


GULTEPE I., OZKAN T., Cetin G.

BEZMIALEM SCIENCE, cilt.5, ss.47-49, 2017 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 5 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.14235/bs.2016.866
  • Dergi Adı: BEZMIALEM SCIENCE
  • Sayfa Sayısı: ss.47-49

Özet

Monoclonal B-cell lymphocytosis is accepted as an important risk factor for developing lymphocytosis familial chronic lymphocytic leukemia (CLL) but does not meet the criteria for B-cell lymphoproliferative disease, and patients with <5,000 ( but not 0) CLL-phenotype B-cell lymphocytes per mm 3. Individuals with lymphocytosis who have relatives diagnosed with CLL should undergo flow cytometry for early diagnosis. In our study, a 56-year-old patient's brother had been early diagnosed with CLL and with lymphocytosis, and the patient was diagnosed with class 1-2 CLL after 2 years. We emphasize that individuals having a family history of CLL should be closely monitored.