A Case of Chronic Lymphocytic Leukemia in Two Brothers

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GULTEPE I., OZKAN T., Cetin G.

BEZMIALEM SCIENCE, vol.5, no.1, pp.47-49, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.14235/bs.2016.866
  • Journal Name: BEZMIALEM SCIENCE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.47-49
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Monoclonal B-cell lymphocytosis is accepted as an important risk factor for developing lymphocytosis familial chronic lymphocytic leukemia (CLL) but does not meet the criteria for B-cell lymphoproliferative disease, and patients with <5,000 ( but not 0) CLL-phenotype B-cell lymphocytes per mm 3. Individuals with lymphocytosis who have relatives diagnosed with CLL should undergo flow cytometry for early diagnosis. In our study, a 56-year-old patient's brother had been early diagnosed with CLL and with lymphocytosis, and the patient was diagnosed with class 1-2 CLL after 2 years. We emphasize that individuals having a family history of CLL should be closely monitored.