Beyond anti-microbial properties: The role of cathelicidin in allergic rhinitis

DILEK F., Gultepe B. , OZKAYA E. , YAZICI M., GEDIK A. H. , CAKIR E.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.44, ss.297-302, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 44 Konu: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.aller.2015.07.006
  • Dergi Adı: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Sayfa Sayısı: ss.297-302

Özet

Background: Cathelicidin, an anti-microbial peptide, is a component of the innate immune system. Cathelicidin has anti-microbial, anti-inflammatory and immunoregulatory functions. Knowledge about the role of the innate immune system in the pathogenesis of allergic diseases has expanded in recent years. We measured levels of the LL-37 peptide in the nasal fluids of children with allergic rhinitis (AR) and investigated the possible role of this peptide in the pathogenesis of AR.