Determination of sulfonamides in milk by ID-LC-MS/MS


Unsal I. A. , Tasan M., GOKCEN T., Goren A. C.

JOURNAL OF CHEMICAL METROLOGY, cilt.12, ss.70-78, 2018 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 12 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.25135/jcm.13.18.04.081
  • Dergi Adı: JOURNAL OF CHEMICAL METROLOGY
  • Sayfa Sayısı: ss.70-78

Özet

In this study, an ID-LC-MS method was developed and validated for the determination of 14 sulfonamides in milk samples. Recovery results were found to be in the range of 91%-114% for milk samples. The relative measurement uncertainty was between 7.5%-12.7%. Validated method was performed on milk samples obtained from market and street vendors. The amount of sulfonamides in the analyzed samples was found to be below the legal limits (Sulfamethazine: 6.46 +/- 0.76 ng/g and sulfisoxazole: 7.3 +/- 0.71 ng/g).