Effects of beta-glucan on protection of young and aged rats from renal ischemia and reperfusion injury


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ESREFOGLU M. , Tok O. E. , AYDIN M. S. , Iraz M., OZER O. F. , SELEK S. , et al.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.117, ss.530-538, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 117 Konu: 9
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4149/bll_2016_105
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayısı: ss.530-538

Özet

BACKGROUND: Ischemia reperfusion injury is one of the leading causes of acute renal failure which is a common clinical event leading to development of chronic kidney disease and a high mortality; especially in elderly people. beta-glucans are glucose polymer groups with free-radical scavenger, macrophage activator, and immune defense inducer functions. We designed this study to determine the possible protective effects of beta-glucan against renal ischemia reperfusion injury comparatively in young and aged rats.