Effects of beta-glucan on protection of young and aged rats from renal ischemia and reperfusion injury

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ESREFOGLU M., Tok O. E., AYDIN M. S., Iraz M., OZER O. F., SELEK S., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.117, no.9, pp.530-538, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 117 Issue: 9
• Publication Date: 2016
• Doi Number: 10.4149/bll_2016_105
• Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.530-538
• Bezmialem Vakıf University Affiliated: Yes

Abstract

BACKGROUND: Ischemia reperfusion injury is one of the leading causes of acute renal failure which is a common clinical event leading to development of chronic kidney disease and a high mortality; especially in elderly people. beta-glucans are glucose polymer groups with free-radical scavenger, macrophage activator, and immune defense inducer functions. We designed this study to determine the possible protective effects of beta-glucan against renal ischemia reperfusion injury comparatively in young and aged rats.