Spectrofluorimetric Method for the Determination of Tolterodine In Human Plasma and Pharmaceutical Preparations by Derivatization with Dansyl Chloride


TEKKELİ Ş. E.

BEZMIALEM SCIENCE, cilt.5, sa.2, ss.50-55, 2017 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.14235/bs.2016.500
  • Dergi Adı: BEZMIALEM SCIENCE
  • Sayfa Sayıları: ss.50-55

Özet

Objective: Tolterodine (TOL) is an anti-muscarinic drug used for the symptomatic treatment of urinary incontinence. Analytical methods in the literature are not sensitive enough for the assay of drug substance biological fluids. To make up the deficit, we developed a sensitive, cost-reduced spectrofluorimetric method for the determination of TOL in plasma and pharmaceutical preparations.