Usefulness of serum M30 and M65 levels to predict response to neoadjuvant chemotherapy in patients with breast cancer.


Turk H. M. , Aliyev A., Celik R., Seker M. , Coban E., Demir T., ...Daha Fazla

Current problems in cancer, cilt.44, sa.1, ss.100497, 2020 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Konu: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.currproblcancer.2019.06.009
  • Dergi Adı: Current problems in cancer
  • Sayfa Sayıları: ss.100497

Özet

Objective: M30 and M65 levels reflect tumor cell activity in patients with epithelial cancer. Cytokeratin 18 is one of the cell skeletal elements. M30 is a apoptotic marker of cytokeratin 18. M65 levels are both an apoptosis and a necrosis marker. The aim of our study was to determine the predictive value of M30 and M65 levels in neoadjuvant treatment of breast cancer.