Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol

Balli, UMUT; Cetinkaya, Burcu; Keles, Gonca; Keles, Zeynep; Guler, Sevki; Sogut, Mehtap; Erisgin, Zuleyha

doi:10.5051/jpis.2016.46.2.84

Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol

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Balli U., Cetinkaya B. O., Keles G. C., Keles Z. P., Guler S., Sogut M. U., ...More

JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, vol.46, no.2, pp.84-95, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 46 Issue: 2
Publication Date: 2016
Doi Number: 10.5051/jpis.2016.46.2.84
Journal Name: JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.84-95
Bezmialem Vakıf University Affiliated: No

Abstract

Purpose: The objective of this study was to investigate the effect of a dietary flavonoid, kaempferol, which has been shown to possess antiallergic, anti-inflammatory, anticarcinogenic, and antioxidant activities on the periodontium by histomorphometric analysis and on gingival tissue matrix metalloproteinase-1 (MMP-1), MMP-8, and tissue inhibitor of metalloproteinase-2 (TIMP-2) by biochemical analysis of rats after experimental periodontitis induction.