Rapid improvement in visual loss with cabergoline treatment in a giant prolactinoma case: 5 years survey

Tasan E. , HANIMOGLU H., Turgut S. , Ilhan M. M. , EVRAN S., KAYNAR M. Y.

NEUROENDOCRINOLOGY LETTERS, cilt.36, sa.1, ss.28-30, 2015 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Konu: 1
  • Basım Tarihi: 2015
  • Sayfa Sayıları: ss.28-30


Giant prolactinoma is a rare subset of macroadenomas. Limited studies demonstrated which therapy could be successfully used in the first-line therapy of giant prolactinoma. We presented a case with a 54x40x40 mm pituitary adenoma and optic chiasmatic compression with left sphenoid sinus invasion. The tumor caused a loss of visual field of the right side. Cabergoline treatment was started with dose of 1.5 mg/week. Fifteen days later, the clinical visual acuity examination showed a significant improvement in the patient with visual field defect. After the five years follow-up magnetic resonance imagining showed reduction of the adenoma size (17x12 mm) was significant. Our findings suggest that, cabergoline can be used as a first-line therapy in giant prolactinomas because tumoral shrinkage without a surgical procedure and rapid improvement in visual field defect is achieved with this medical treatment.