The relationship between FGF-23 and ghrelin levels in CKD patients: preliminary data

OZTURK S., OZKAN O., EFE M., Yazici H., Gursu M., Kaya A. H., ...More

MINERVA UROLOGICA E NEFROLOGICA, vol.68, no.2, pp.227-232, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 2
  • Publication Date: 2016
  • Journal Name: MINERVA UROLOGICA E NEFROLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.227-232
  • Keywords: Fibroblast growth factor 23, Ghrelin, Renal insufficiency, chronic, Uremia, RENAL-FAILURE, HYPERPHOSPHATEMIA, ATHEROSCLEROSIS, HEMODIALYSIS, ASSOCIATION, STOMACH
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

BACKGROUND: Fibroblast growth factor (FGF)-23 is a recently discovered phosphaturic hormone that increases in chronic kidney disease (CKD). It has been accepted as a determinant of mortality and a therapeutic target in these patients. Ghrelin is a hormone that has roles in energy and nutrient metabolism. Ghrelin level was found to be increased in CKD patients. This is a controlled study in which the relationship between FGF-23 and ghrelin levels in CKD patients has been studied.