Structure elucidation of organic compounds from natural sources using 1D and 2D NMR techniques

Topcu G., ULUBELEN A.

JOURNAL OF MOLECULAR STRUCTURE, vol.834, pp.57-73, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 834
  • Publication Date: 2007
  • Doi Number: 10.1016/j.molstruc.2006.12.001
  • Journal Name: JOURNAL OF MOLECULAR STRUCTURE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.57-73
  • Keywords: Labiatae family plants, terpenoids, diterpenoids, structure elucidation, NMR and other spectroscopic techniques, REARRANGED ABIETANE DITERPENES, STOECHAS SSP STOECHAS, SALVIA-CANDIDISSIMA, NEOCLERODANE DITERPENOIDS, TEUCRIUM-ALYSSIFOLIUM, SIDERITIS-TROJANA, AERIAL PARTS, CONSTITUENTS, TERPENOIDS, 5,9-DEHYDRONEPETALACTONE
  • Bezmialem Vakıf University Affiliated: No

Abstract

In our continuing studies on Lamiaceae family plants including Salvia, Teucrium, Ajuga, Sideritis, Nepeta and Lavandula growing in Anatolia, many terpenoids, consisting of over 50 distinct triterpenoids and steroids, and over 200 diterpenoids, several sesterterpenoids and sesquiterpenoids along with many flavonoids and other phenolic compounds have been isolated. For Salvia species abietanes, for Teucrium and Ajuga species neo-clerodanes for Sideritis species ent-kaurane diterpenes are characteristic while nepetalactones are specific for Nepeta species. In this review article, only some interesting and different type of skeleton having constituents, namely rearranged, nor-or rare diterpenes, isolated from these species will be presented. For structure elucidation of these natural diterpenoids intensive one- and two-dimensional NMR techniques (H-1, C-13 APT, DEPT, NOE/NOESY, H-1-H-1 COSY, HETCOR, COLOC, HMQC/HSQC, HMBC, SINEPT) were used besides mass and some other spectroscopic methods. (C) 2007 Published by Elsevier B.V.