Impact of Copper and Oxidative Stress Index Levels on Insulin Resistance, Lipid Profile and Hormonal Status of Patients with Polycystic Ovary Syndrome

ATAKUL N., SELEK Ş., KÖKTAŞOĞLU F., KILIÇ B. Ş., GÜL A. Z., ATAMER Y.

ISTANBUL MEDICAL JOURNAL, cilt.23, 2022 (ESCI, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/imj.galenos.2022.28445
  • Dergi Adı: ISTANBUL MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Anahtar Kelimeler: Polycystic ovary syndrome, copper, oxidative stress, testosterone, SYNDROME PCOS, WOMEN, MARKERS, PARAMETERS, PHENOTYPES, CAPACITY, METALS
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine abnormalities of reproductive age and has a highly heterogeneous nature regarding its multisystemic symptoms. To elicit pathophysiological roots, metabolic mapping and between-correlations among key parameters are of vital importance. We generated a platform including cardinal hormones, lipids, homeostasis model assessment of insulin resistance (HOMA-IR) and oxidative markers [total-oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), copper (Cu)] related to pathophysiology.