Purpose: The purpose of this study was to evaluate the effect of the different color of resin cements and zirconia cores on the translucency parameter (TP) of the restoration that simulates the implant-supported fixed prosthesis using titanium base on the bottom. Materials and Methods: Zirconia core plates (Zr-Zahn) were prepared in A2 shades (n = 11). Resin cement plates (3M ESPE) were prepared in A2, A1, translucent (TR) shades (n = 11). The initial color measurements and were measured on zirconia core plates, and resin cements plates using a spectrophotometer. Then, the resin cement plates were placed below the zirconia core plates, and the second measurements were done. The final measurements were done after placing the titanium discs in the bottom. The data were analyzed with two-way analysis of variance and Tukey honestly significant differences tests (alpha = 0.05). Results: The highest TP values were recorded for A1-colored resin specimens and the lowest for zirconia core plates in the first measurement (P < 0.05). The addition of zirconia core decreased the TP values in all tested resin cement groups (P < 0.05). The highest TP value was recorded for A1-colored resin cement with zirconia core plates and the lowest for A2 and TR with zirconia core plates after second measurements (P < 0.05). The addition of titanium decreased the TP of the zirconia core plate and resin cement combination (P < 0.05). Conclusions: The addition of a zirconia core under the resin cement dramatically reduced the TP values, and the presence of a titanium layer decreased the TP value and caused a darker appearance.