Cytotoxic activity and essential oil composition of leaves and berries of Juniperus excelsa

Topcu G., GOREN A. C., BILSEL G., BILSEL M., CAKMAK O., SCHILLING J., ...More

PHARMACEUTICAL BIOLOGY, vol.43, no.2, pp.125-128, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 2
  • Publication Date: 2005
  • Doi Number: 10.1080/13880200590919429
  • Journal Name: PHARMACEUTICAL BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.125-128
  • Bezmialem Vakıf University Affiliated: No

Abstract

The composition of the water-distilled essential oils of the berries and leaves of Juniperus excelsa M. Bieb. were analyzed by gas chromatography-mass spectrometry (GCMS). The main components in the berries of J. excelsa, accounting for 56.1% of the oil, were determined as alpha-pinene (34.0%), cedrol (12.3%), L-verbenol (5.4%), and D-verbenol (4.4%) while in the leaves of J. excelsa, accounting for 63.2% of the oil, were found to be alpha-pinen (29.7%), cedrol (25.3%), alpha-muurolene (4.4%), and 3-carene (3.8%). Cytotoxic and antimicrobial potential of the berries and leaves of J. excelsa were investigated.