Effects of Cilostazol on Oxidative Stress, Systemic Cytokine Release, and Spinal Cord Injury in a Rat Model of Transient Aortic Occlusion


Kurtoglu T., Basoglu H. , Ozkisacik E. A. , Cetin N. K. , Tataroglu C., Yenisey C., ...More

ANNALS OF VASCULAR SURGERY, vol.28, no.2, pp.479-488, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.1016/j.avsg.2013.08.005
  • Title of Journal : ANNALS OF VASCULAR SURGERY
  • Page Numbers: pp.479-488

Abstract

Background: Cilostazol is a phosphodiesterase inhibitor that has anti-inflammatory potential in addition to vasodilator and antiplatelet effects. The aim of this study was to determine the influence of cilostazol on biochemical markers of oxidative damage, proinflammatory cytokine release, and spinal cord injury after transient aortic occlusion in rats.