Extreme elevation of serum alpha fetoprotein in decompensated cirrhosis without HCC: an ominous sign


Senturk H. , Cumali R.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, vol.22, no.1, pp.19-23, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.5301/jbm.2008.1034
  • Title of Journal : INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS
  • Page Numbers: pp.19-23

Abstract

Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.