Extreme elevation of serum alpha fetoprotein in decompensated cirrhosis without HCC: an ominous sign

Senturk H., Cumali R.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, vol.22, no.1, pp.19-23, 2007 (SCI-Expanded) identifier identifier identifier


Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.