Extreme elevation of serum alpha fetoprotein in decompensated cirrhosis without HCC: an ominous sign

Senturk H., Cumali R.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, cilt.22, sa.1, ss.19-23, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.5301/jbm.2008.1034
  • Dergi Adı: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.19-23
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.