Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude


Guvenc T. S. , HÜSEYİNOĞLU N., Ozben S., Kul S., Cetin R., Ozen K., ...More

SLEEP AND BREATHING, vol.20, no.1, pp.5-13, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1007/s11325-015-1175-1
  • Title of Journal : SLEEP AND BREATHING
  • Page Numbers: pp.5-13

Abstract

Purpose Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.