Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude

Guvenc T. S., HÜSEYİNOĞLU N., Ozben S., Kul S., Cetin R., Ozen K., ...Daha Fazla

SLEEP AND BREATHING, cilt.20, sa.1, ss.5-13, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s11325-015-1175-1
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5-13
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

Purpose Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.