Right ventricular geometry and mechanics in patients with obstructive sleep apnea living at high altitude

Guvenc T. S., HÜSEYİNOĞLU N., Ozben S., Kul S., Cetin R., Ozen K., ...More

SLEEP AND BREATHING, vol.20, no.1, pp.5-13, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1007/s11325-015-1175-1
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.5-13
  • Bezmialem Vakıf University Affiliated: Yes


Purpose Repetitive obstruction of larynx during sleep can lead to daytime pulmonary hypertension and alterations in right ventricular morphology and function in a small fraction of obstructive sleep apnea syndrome (OSAS) patients. Environmental effects, particularly high altitude, can modify the effects of OSAS on pulmonary circulation, since altitude-related hypoxia is related with pulmonary vasoconstriction. This potential interaction, however, was not investigated in previous studies.