Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia

ECE A., UYANIK B., Iscan A., ERTAN P., YIGITOGLU M.

BIOLOGICAL TRACE ELEMENT RESEARCH, vol.59, pp.31-39, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59
  • Publication Date: 1997
  • Doi Number: 10.1007/bf02783227
  • Journal Name: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.31-39
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

In order to evaluate serum copper and zinc status in children with iron deficiency anemia (IDA), 60 children with IDA aged 1-14 yr and 64 healthy children as controls aged 1-14 yr were included the study. Serum copper levels were higher in children with TDA (189 +/- 49 mu g/dL) than those of controls (163 +/- 37 mu g/dL) (p = 0.001). Serum zinc levels were lower in the patient group (109 +/- 59 mu g/dL) than those of control subjects (135 +/- 56 mu g/dL) (p = 0.017). Ln addition, there were statistically significant negative correlations between hematological parameters and serum copper levels in the patient group, but not in controls. No correlation between hematological parameters and serum-zinc levels were found in both patient and control groups, except positive correlation between mean corpuscular volume (MCV) and serum zinc level in patients.