Diffusion tensor imaging findings in the hunger and satiety centers of the brain after bariatric surgery: a preliminary study.

Yurtsever İ., Atasoy B., Bozkurt S., Yıldız G. B., Balsak S., Yabul F., ...Daha Fazla

Irish journal of medical science, cilt.193, sa.1, ss.191-197, 2024 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 193 Sayı: 1
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1007/s11845-023-03389-4
  • Dergi Adı: Irish journal of medical science
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, CAB Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.191-197
  • Anahtar Kelimeler: Bariatric surgery, Diffusion tensor imaging, Morbid obesity, Obesity
  • Bezmiâlem Vakıf Üniversitesi Adresli: Evet

Özet

PurposeTo investigate the alterations in the diffusion tensor imaging (DTI) parameters measured in the hunger and satiety centers of the brain before and after bariatric surgery (BS) in morbidly obese patients.MethodsFourty morbidly obese patients were evaluated before and after BS. Mean diffusivity (MD) and fractional anisotropy (FA) values were calculated from 14 related brain locations, and the DTI parameters were analyzed.ResultsAfter the BS, the mean BMI of the patients decreased from 47.53 +/- 5.21 to 31.48 +/- 4.21. The MD and FA values in the all of the hunger and satiety centers was found statistically significant different in the pre-surgery period compared to the post-surgery period (for each; p-value < 0.001).ConclusionThe FA and MD changes after BS may be attributed to reversible neuroinflammatory alterations in the hunger and satiety centers. Decreased MD and FA values after BS may be explained by the neuroplastic structural recovery in the related brain locations.