Oxidative stress in obese children and its relation with insulin resistance

Ozgen I. T., TASCILAR M. E., Bilir P., BOYRAZ M., GUNCIKAN M. N., AKAY C., ...More

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, vol.25, pp.261-266, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25
  • Publication Date: 2012
  • Doi Number: 10.1515/jpem-2011-0397
  • Journal Name: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.261-266
  • Keywords: glutathione peroxidase, insulin resistance, nitrite/nitrate, obesity, oxidative stress, ENDOTHELIAL DYSFUNCTION, DIABETES-MELLITUS, GLUTATHIONE, PLASMA, INFLAMMATION, PARAMETERS, GLUCOSE, ENZYMES, GROWTH
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

Background: In obese populations, oxidative stress plays a major role in the pathogenesis of serious diseases such as diabetes, coronary heart disease, and atherosclerosis. In this study, we investigated the status of oxidative stress in obese children as to nitrite/nitrate and glutathione peroxidase levels, and their relation with insulin resistance (IR).