Vitamin C modulates oxidative stress-induced colitis in rats

Zerin M., Karakilcik A. Z., Bitiren M., Musa D., Ozgonul A., Selek S., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.40, no.6, pp.871-879, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 6
  • Publication Date: 2010
  • Doi Number: 10.3906/sag-0905-6
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.871-879
  • Bezmialem Vakıf University Affiliated: No

Abstract

Aim: Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aimed to investigate the probable protective effects of vitamin C on oxidative injury in rats in which colitis was experimentally induced with acetic acid.