Cilostazol and Diltiazem Attenuate Cyclosporine-Induced Nephrotoxicity in Rats


Gokce M., Yuzbasioglu M. F. , Bulbuloglu E. , Oksuz H., Yormaz S., Altinoren O., ...More

TRANSPLANTATION PROCEEDINGS, vol.44, no.6, pp.1738-1742, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1016/j.transproceed.2012.04.025
  • Title of Journal : TRANSPLANTATION PROCEEDINGS
  • Page Numbers: pp.1738-1742

Abstract

Aim. Cyclosporine (CsA), an important agent used in organ transplantation to prevent rejection, displays nephrotoxicity as the most important side effect limiting usage. In this study, we sought to evaluate the effects of cilostazol and diltiazem to counter the nephrotoxicity induced by the calcineurin inhibitor CsA.