Cilostazol and Diltiazem Attenuate Cyclosporine-Induced Nephrotoxicity in Rats

Gokce M., Yuzbasioglu M. F., Bulbuloglu E., Oksuz H., Yormaz S., Altinoren O., ...More

TRANSPLANTATION PROCEEDINGS, vol.44, no.6, pp.1738-1742, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1016/j.transproceed.2012.04.025
  • Journal Name: TRANSPLANTATION PROCEEDINGS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1738-1742
  • Bezmialem Vakıf University Affiliated: No

Abstract

Aim. Cyclosporine (CsA), an important agent used in organ transplantation to prevent rejection, displays nephrotoxicity as the most important side effect limiting usage. In this study, we sought to evaluate the effects of cilostazol and diltiazem to counter the nephrotoxicity induced by the calcineurin inhibitor CsA.