A case-control study on effects of the ATM, RAD51 and TP73 genetic variants on colorectal cancer risk


Yazici M. , Yilmaz U., Yilmaz N., Celik F., Isikoren E. G. , Celikel B., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.44, pp.778-786, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44
  • Publication Date: 2019
  • Doi Number: 10.1515/tjb-2019-0222
  • Title of Journal : TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Page Numbers: pp.778-786

Abstract

Aim: ATM, RAD51 and TP73 are genes that take part in DNA repair pathways. The aim of this prospective case-control study was to determine the genotype and allele distributions of the ATM 5'-UTR G/A, RAD51 135 G/C and TP73 GC/AT polymorphisms and their relationship with clinical parameters in Turkish colorectal cancer (CRC) patients.