Age-related distribution of basal anti-mullerian hormone levels in a population of infertile women İnfertil kadınlarının bazal anti-müllerian hormon serum seviyelerinin yaşa özgü dağılımı

Creative Commons License

Ozcan P., Ficicioglu C., Yesiladali M., Devranoglu B., AYDIN S., Batmaz G.

Journal of Clinical and Analytical Medicine, vol.7, no.3, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.4328/jcam.3399
  • Journal Name: Journal of Clinical and Analytical Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Keywords: Anti-Mullerian Hormone, Reproductive Age, Age-Specific Values, ANTIMULLERIAN HORMONE, OVARIAN RESERVE, MENSTRUAL-CYCLE, INHIBIN-B, SERUM, MARKER, FSH
  • Bezmialem Vakıf University Affiliated: Yes

Abstract

© 2016, Journal of Clinical and Analytical Medicine. All rights reserved.Aim: We aimed to constitute age-specific reference serum values for anti- Mullerian Hormone (AMH) in women, and to analyze the distribution of basal serum AMH levels in Turkish women of reproductive age attending an infertility clinic to provide a framework for expected values according to age. Material and Method: Retrospective analysis of prospectively collected data on cycle day 2-3 serum AMH measurements of 409 women attending a single infertility unit in Turkey through a 12-month-period was performed. Results: Concentrations of serum AMH were shown to decrease with advancing age of the female partner. The mean age of the women was 34.04±5.39 years and the mean AMH level of the women was 1.77±1.82. The AMH levels were grouped according to age as follows: 20-24, 25-29, 30-34,35-39, and >40 years. The median AMH values were 2.16 ng/ml, 2.15 ng/ml, 1.71 ng/ml, 0.80 ng/ml, and 0.47 ng/ml, respectively according to the age groups. Discussion: The present data provide a framework for age-specific serum AMH levels in a Turkish population of infertile women.