Two Cases Of Acute Myeloid Leukemia (AML) Who Had Diagnosed Due To Gingival Hyperplasia

Yücesoy T., Doğruel F., Yaşar M. T., Guliyev E., Alkan A.

AÇBİD- 10th International Congress- 2016, Antalya, Turkey, 11 - 15 May 2016, pp.268

  • Publication Type: Conference Paper / Summary Text
  • City: Antalya
  • Country: Turkey
  • Page Numbers: pp.268
  • Bezmialem Vakıf University Affiliated: Yes


One of the first signs of acute myeloid/myelogenous leukemia (AML) may be gingival hyperplasia disease about 3 -5 %. The most common leukemic infiltration of the gingiva are observed with AML, M4 (acute myelomonocytic leukemia) and M5 (acute monocytic leukemia) subtypes. Here we report two patients who applied to our hospital with severe complaints of hiperplastic gingiva, spontaneous bleeding and pain. Patients also had suffered from persistant infection for months and antibiotic therapy and pain killers had been applied to the both patients by different clinics and hosptitals. But reduction of the patient›s complaints were not observed, patients were sent to our clinic. The swollen, red, painful and easy bleeding mucous membrane structure was observed as a result of physical examination. The patients were also suffering from weakness and fatigue. According to existing symptoms, we had done several hemogramme and biochemical tests on patient and the results made us consider AML and because of that the patients were consulted to Hematology – Oncology Department of Erciyes University. Bone marrow aspiration biopsies were performed to the patients who had blast in the peripheral blood smear. As a result of bone marrow biopsies, AML were diagnosed for both patients and right after that the patient had chemotherapy treatment. Gingival hyperplasia may develop because of many reasons. As in these cases, exhaustive examinations and consultations on diagnose of AML must be done in terms of fast-growing and spontaneous gingival bleeding. As clinicians, we must always be aware of the symptoms of AML and take adequate blood tests when necessary.