AÇBİD- 10th International Congress- 2016, Antalya, Turkey, 11 - 15 May 2016, pp.268
One of the first signs of acute myeloid/myelogenous leukemia (AML) may be gingival hyperplasia
disease about 3 -5 %. The most common leukemic infiltration of the gingiva are observed with
AML, M4 (acute myelomonocytic leukemia) and M5 (acute monocytic leukemia) subtypes.
Here we report two patients who applied to our hospital with severe complaints of hiperplastic
gingiva, spontaneous bleeding and pain. Patients also had suffered from persistant infection
for months and antibiotic therapy and pain killers had been applied to the both patients by
different clinics and hosptitals. But reduction of the patient›s complaints were not observed,
patients were sent to our clinic.
The swollen, red, painful and easy bleeding mucous membrane structure was observed as a
result of physical examination. The patients were also suffering from weakness and fatigue.
According to existing symptoms, we had done several hemogramme and biochemical tests on
patient and the results made us consider AML and because of that the patients were consulted
to Hematology – Oncology Department of Erciyes University. Bone marrow aspiration biopsies
were performed to the patients who had blast in the peripheral blood smear. As a result of
bone marrow biopsies, AML were diagnosed for both patients and right after that the patient
had chemotherapy treatment.
Gingival hyperplasia may develop because of many reasons. As in these cases, exhaustive
examinations and consultations on diagnose of AML must be done in terms of fast-growing
and spontaneous gingival bleeding. As clinicians, we must always be aware of the symptoms
of AML and take adequate blood tests when necessary.